Accurate monitoring of blood pressure is a critical component of patient care. This measurement serves as an indicator of the health of the heart and arteries and is a measure of whether sufficient blood is distributed throughout the body. While blood pressure is considered to be among the most basic of vital signs, common methodologies today are either highly invasive, prone to complications or time-consuming to ensure proper accuracy.
At PyrAmes, we are transforming the delivery of patient care through advanced sensor measurement for cNIBP.
Considered the gold standard, but may be prone to damping effects that affect accuracy.
Complications beyond bleeding risk include: infections, clots, tissue and nerve damage.
Continuous real-time blood pressure, rich hemodynamic information.
Requires placement and maintenance by trained clinicians. May require support from additional medical personnel.
Not as accurate as an arterial line. Can result in elevated BP values due to discomfort for infant patients. 1
Can be disturbing or painful for very young and elderly patients.
Intermittent measurements only. Prolonged use can lead to tissue damage and inaccurate measurements. 4
Prone to incorrect placement and usage.
PTT alone is unreliable in offering full insights into BP variations. 2
Cumbersome and requires the patient to wear multiple sensors.
Can measure continuous blood pressure.
Multiple sensors needed. Added time in attachment and removal. Adhesive can irritate skin.
Similar to arterial lines. 3
Non-invasive, wireless and painless. No needles, eliminating the risk of infection as compared to current methods.
Continuous blood pressure measurements, rich hemodynamic information.
Placement is relatively simple, requires no special training or qualifications for the care team.
PyrAmes platforms will provide options to continuously monitor blood pressure cNIBP for patients of all ages.
could benefit from BP monitoring but would not receive an arterial line because it is invasive and costly.5
50% of adults are affected by high blood pressure in the US, increasing their mortality rates.6
Raised blood pressure (BP) is responsible for 7.6 million deaths worldwide annually.7
cNIBP has the potential for early detection of conditions within preterm infants and adults.
1. Kumar N, Akangire G, Sullivan B, Fairchild K, Sampath V. Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: big data to the forefront. Pediatr Res. 2020 Jan;87(2):210-220. doi: 10.1038/s41390-019-0527-0. Epub 2019 Aug 4. PMID: 31377752; PMCID: PMC6962536.
2. Ding, X., Yan, B.P., Zhang, YT. et al. Pulse Transit Time Based Continuous Cuffless Blood Pressure Estimation: A New Extension and A Comprehensive Evaluation. Sci Rep 7, 11554 (2017). https://doi.org/10.1038/s41598-017-11507-3
3. Quan, X.; Liu, J.; Roxlo, T.; Siddharth, S.; Leong, W.; Muir, A.; Cheong, S.-M.; Rao, A. Advances in Non-Invasive Blood Pressure Monitoring. Sensors 2021, 21, 4273. https://doi.org/10.3390/s21134273
4. Tareerath M, Wongyingsinn M. Comparison of the Incidences of Cuff-Related Trauma after Non-invasive Arterial Blood Pressure Measurement with and without Padding in Patients Undergoing Elective Surgery. J Med Assoc Thai 2018;101:1.
5. Haidari, E. S., Lee, H. C., Illuzzi, J. L., Phibbs, C. S., Lin, H., & Xu, X. (2020). Hospital variation in admissions to neonatal intensive care units by diagnosis severity and category. Journal of Perinatology, doi:10.1038/s41372-020-00775-z