About PyrAmes & Our Technology


Our Platforms

Presenting Boppli

Accurate1, non-invasive, continuous, wireless BP monitoring for neonatal and pediatric patients.

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Presenting Bosimi

Adult inpatient and emergency care cNIBP.

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Presenting Bosimi@Home

Diagnostics, treatment validation & home medical management.

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cNIBP Health Impact

PyrAmes platforms will provide options to continuously monitor blood pressure cNIBP for patients of all ages.

Over 50% of NICU Admissions

could benefit from BP monitoring but would not receive an arterial line because it is invasive and costly.2

50% of Adults have High BP

50% of adults are affected by high blood pressure in the US, increasing their mortality rates.3

7.6 Million Deaths Annually

Raised blood pressure (BP) is responsible for 7.6 million deaths worldwide annually.4

cNIBP & Early Detection

cNIBP has the potential for early detection of conditions within preterm infants and adults.

News & Updates

August 21, 2023

West Coast Pediatrics Consortium recognizes PyrAmes for pediatric medical device innovation

PyrAmes has been awarded a Catalyzing Pediatric Innovation (CPI) grant by the West Coast Consortium for Technology & Innovation in Pediatrics (CTIP), centered at Children's Hospital Los Angeles. Including PyrAmes, only five innovators were selected for developing novel devices and technologies for pediatric patients in CTIP’s seventh annual competition. PyrAmes was selected for its novel approach to monitor the blood pressure of critically-ill, yet stabilized, infants who have not yet been treated for hypotension, by extending the use of its non-invasive, wearable Boppli® device. There were ~3.6 million live U.S. births in 2020, with 9% to 13% requiring NICU care (~400,000), including monitoring of vital signs such as blood pressure. CTIP is a pediatric medical device accelerator centered at Children's Hospital Los Angeles (CHLA) and the University of Southern California (USC). CTIP promotes the commercialization and clinical use of pediatric medical device technology. Its goal is to support innovators and encourage development of safe, effective medical devices designed specifically for pediatric patients.

May 1, 2023

PyrAmes Inc. Announces Investment from March of Dimes to Support Maternal and Pediatric Health Products

CUPERTINO, CA and ARLINGTON, VA — PyrAmes Inc. has received an investment from March of Dimes, the leading organization fighting for the health of moms and babies, to support development and commercialization of its wearable technology to noninvasively monitor blood pressure, particularly for new mothers and their babies. PyrAmes' goal is to develop more convenient, clinically-accurate, blood pressure monitoring for all patients, including both mothers and babies in order to support enhancing their health before and after childbirth. PyrAmes’ Boppli™ device for critically-ill infants received Breakthrough Device Designation from the US Food & Drug Administration (FDA). (more…)

April 27, 2023

International Journal Sensors Highlights PyrAmes’ Technology in Neonatal Clinical Study

PyrAmes’ innovative Boppli™ blood pressure device is featured in the journal Sensors, in a paper reporting a clincal study of 81 infants undergoing critical care at Lucile Packard Children’s Hospital Stanford. Sensors is a leading international, peer-reviewed journal on the science and technology of sensors. The paper, Clinical Study of Continuous Non-Invasive Blood Pressure Monitoring in Neonates, highlights the performance of PyrAmes’ novel algorithm-based blood pressure sensor. Boppli is designed to meet the blood pressure monitoring requirements and physical dimensions of small, prematurely-born infants, without external calibration. Boppli uses machine-learning techniques to extract blood pressure values from the shape of the pulse waveform, and is currently being considered for market clearance by the FDA as a Class II medical device. The paper indicates the use of Boppli is feasible for critically ill term and preterm infants with a wide variety of pathologies—from serious cardiac ailments, pre- and post-operative cases, neurologic conditions, and prematurity.

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2020 FDA Breakthrough Device Designation


Founding Member of CDC National Hypertension Control Roundtable


2020 SWPDC Pediatric Device Award, Member of SWPDC


2019 MedTech Innovator Accelerator & 2020 NCC-PDI MedTech Innovator Pediatric Accelerator


Exponential Medicine 2019 One to Watch Award